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Low molecular weight complexes contained IGF-I or IGF-II bound to an insulin regulated liver derived protein IGFBP-1 (17, 18), at first called the 28 kDa binding protein or PP12 (19)

Our result is compliant with data concerning the vitamin B 12 intake in athletes, which ranges from 2.5 g/d to 11 g/d, being at a lower level in vegetarians and vegans, whereas the recommended daily intake of cobalamin in adults is 2.4 g/day [31,32,33,34,35,36]

In summary, accurate assessment of vitamin B12 status is problematic, and there is no consensus as to the best biomarker or combination of biomarkers to use

The profound decline in NAD+ levels during aging and its restoration through various precursor compounds has positioned NAD+ at the forefront of longevity research and research development, offering unprecedented opportunities to address age-related decline and promote healthy aging through metabolic optimization

No single strict definition exists, but many studies use parameters of low mean arterial pressure (MAP) 2.2L/kg/m2 [1,3]